Director, PK/PD Modelling and Simulation Group Head

Location Kingdom of Belgium
Discipline: Pre-Clinical Development
Job type: Permanent
Salary: £Salary: On application
Contact name: Tom Douglas

Contact email: tom.douglas@rbwconsulting.com
Contact phone: 01293 584300
Job ref: 20021
Published: 29 days ago
Expiry date: 12 April 2021

​The Preclinical team at RBW are working in close partnership with a world-renowned organisation that require a leader for their discovery PK/PD modelling and simulation team. This is a fantastic opportunity for a highly experienced scientist that is looking for the next step in their career to lead and build your own team of modellers. You will be required to drive preclinical PK/PD strategies from early discovery to first in human studies.

Responsibilities:

  • Implement modelling and simulation approaches including PK/PD, PBPK and quantitative systems pharmacology.

  • Act as project lead for DMPK and interact with multidisciplinary areas to implement the correct ADME studies.

  • Design of in vivo PK/PD studies using modelling techniques.

  • Guide dose selection and predict first in human pharmacokinetic profile.

  • Develop in vitro to in vivo correlation techniques.

Requirements:

  • Educated to PhD with a minimum of 10 years industry experience.

  • Sufficient knowledge using software including NONMEM, R, Phoenix WinNonlin, Gastroplus etc.

  • Significant experience in DMPK and drug discovery with a focus on modelling and simulation is required.

  • Strong communication skills to interact with key opinion leaders.

  • Extensive publication list outlining your work in the DMPK field.

Salary: On application