Director - RNA Biology

Location Boston
Discipline: Pre-Clinical Development
Job type: Permanent
Salary: £Salary: $Strong salary, bonus, equity and supporting package.
Contact name: Surbhi Dhar

Contact email: surbhi.dhar@rbwconsulting.com
Contact phone: 16179821238
Job ref: ​21522
Published: about 1 month ago
Expiry date: 17 June 2021

Location: Greater Boston, USA

Type: Full Time Permanent

A unique start-up with a breakthrough RNA-targeting platform is seeking a highly motivated individual to lead their RNA Biology efforts. This role comes with an opportunity to lead a group of highly talented scientists and projects from the outset. The company has programs in Oncology, Neurology and Rare Disease indications. It boasts of a highly energetic, collaborative, and progressive environment with stellar cofounders and leaders on the advisory board.

Responsibilities:

  • Lead drug discovery, proof of concept and target identification efforts using RNA Biology and Therapeutic Platform development experience

  • Lead efforts towards the development, characterization, and execution of in vitro and cell-based assays for Hit to Lead (HTL) and Mechanism of Action (MoA) studies

  • Bring scientific and strategic leadership for scientists in the team, be their mentor and lead from the front

  • Bring a sense of innovation towards answering important RNA biology questions using cutting edge technologies like NGS, ribosome profiling, reporter, and mRNA based assays

  • Foster, nurture and leverage constructive relationships across other internal functional groups

  • Actively collaborate with internal and external partners to achieve key objectives

Requirements:

  • PhD in RNA biology, Molecular Biology, Genetics, Biochemistry or a related discipline

  • • At least 5-6 years of industry experience leading drug discovery programs in a start-up biotech or pharma company. RNA targeting or small molecule experience will be preferred

  • • Prior people and project management experience is required

  • • Prior experience with RNA biology, especially with mRNA biology like splicing, decay, degradation, regulation and RNA-protein interaction is a must

  • • Expertise in molecular biology techniques like RNA-seq/NGS, RT-qPCR, RNA-IP, ribosome profiling and reporter assays

  • • Exceptional communication skills, both written and oral, and an ability to communicate complex issues to a range of audience

  • • Ability to champion innovation across the board to drive organizational improvement is encouraged

I manage a range of other permanent and contract positions for a broad portfolio of clients (Biotech, CRO and Pharma). If the above role isn’t for you but you’d nevertheless like to discuss your options in the market, I’d welcome a confidential discussion by phone or email. Contact Surbhi Dhar at +1 (617) 982 1238 or surbhi.dhar@rbwconsulting.com

Salary: $Strong salary, bonus, equity and supporting package.