Principal Scientist, Immunooncology – Antibody Therapy Company

Location Boston, Suffolk, Massachusetts
Discipline: Pre-Clinical Development
Job type: Permanent
Salary: £$Strong salary, bonus, equity and supporting package
Contact name: Surbhi Dhar

Contact email:
Contact phone: +1 (617) 982 1238
Job ref: 21997
Published: about 2 months ago
Expiry date: 31 August 2021

Company Overview

·         A well-funded, clinical stage biopharma company with a novel Antibody Therapy platform is seeking a highly motivated individual with experience in assay development and management. The company's proprietary platform has made significant development in the treatment of Immunooncological indications. The company is innovative, encourages diversity and has highly progressive values.



·         Develop robust and reproducible cellular assays to evaluate activity of drug candidates

·         Conduct well controlled decision-making in vivo experiments to demonstrate preclinical proof-of-principle for novel immuno-oncology agents

·         Apply deep understanding of immune readouts (i.e., FACS-based immunophenotyping, T cell activation assays, cytokine profiling, immunohistochemistry, mRNA profiling, etc.) to elucidate mechanism of action and identify candidate biomarkers

·         Direct scientifically and train junior scientists on both in vivo and in vitro techniques

·         Manage daily activities of one or two senior scientists/scientists

·         Serve as a point of contact for collaborations with external academic and corporate partners and CROs

·         Lead multidisciplinary discovery project teams and design strategies for demonstrating preclinical proof-of-principle for novel immuno-oncology agents

·         Keep abreast with cutting-edge research and competitive intelligence and apply to concept discovery and drug candidate characterization in the field of cancer immunotherapy

·         Participate in authorship of scientific and/or patent publications

·         Prepare and present data to internal and external audiences

·         Facilitate productive interactions with neighboring functions in the Drug Discovery and Immunology groups within Compass Therapeutics



·         PhD and a post-doctoral training in immunology / immuno-oncology with evidence of high scientific achievements

·         3 to 5+ years of managerial experience is preferred

·         Strong immunology background

·         Strong publication record

·         Track record of scientific excellence and successful advancement of new therapeutic principles in industry or academia

·         Ability to design and perform hands on reproducible, well controlled, decision making experiments

·         Management experience; teach and direct young scientists and technical personnel

·         Ability to write technical scientific documents independently

·         Experience in evaluating the activity of immuno-oncology agents in preclinical models

·         Be a highly collaborative team player

 I manage a range of other permanent and contract positions for a broad portfolio of clients (Biotech, CRO and Pharma). If the above role isn’t for you but you’d nevertheless like to discuss your options in the market, I’d welcome a confidential discussion by phone or email. Contact Surbhi Dhar at +1 (617) 982 1238 or