Research Scientist - Virology

Location Oxford
Job type: Permanent
Contact name: Thomas Urwin

Contact email:
Job ref: 27556
Published: 11 months ago
Expiry date: 26 Jul 2023 11:59

Research Scientist - Virology 

Harwell, Oxford

Competitive Salary


RBW Consulting are delighted to be partnered with a clinical stage T cell immunotherapy company developing products to treat and prevent cancer and infectious diseases. They currently have a Phase 2 clinical trial for prostate cancer and a Phase 1 clinical program for chronic HBV. 


An opportunity has arised to join a team that is focused on therapeutic vaccine research and development. The successful candidate will participate in the development of new approaches to generate immunotherapeutics against infectious disease and cancer. 


  • Give input to the strategy and develop and conduct laboratory work involved in the design, construction, growth, and evaluation of viral vector vaccine candidates
  • Keep up to date on the field of immunotherapeutics, and review and suggest new approaches, alternative laboratory methods, or new studies to improve the outcome of a given objective
  • Perform quality control assays on research-grade viral vectored vaccine preparations (physical titer, infectious titer, sequence verification, transgene expression)
  • Maintain and evaluate both mammalian and bacterial cell cultures for growth conditions, DNA purification and viral vector production, and interpret and present the data in a concise and orderly fashion.
  • Assist in studies to optimise the ability to manufacture viral-vectored vaccines, such as evaluation of alternative transfection systems, host or vector gene deletions or insertions, viral culture yield, systems for viral growth, etc.
  • Evaluate and perform analytic assays to determine the quality, yield, stability, etc. of specific candidates or of specific manufacturing process conditions as required
  • Assist in ordering supplies, making reagents and maintaining the laboratory in order to conduct necessary experiments.
  • Work under GRP (good research practice) conditions, with the appropriate requisite training and documentation
  • Participate in the development and conduct of laboratory meetings, and give presentations inside and outside the company as required
  • Attend at least one relevant scientific meeting/course per year to continue educational advancement.



  • Master’s degree plus 4 years of laboratory experience, or a recent PhD, in virology/molecular biology
  • Relevant work experience, with demonstrated experience in laboratory bench work with molecular biology and cell and virus culture systems
  • Proficiency in designing experiments and conducting research using a variety of methodologies; e.g. design and cloning of mammalian expression cassettes, PCR, DNA sequence interpretation, ELISA, western blot, viral growth curves, viral titers, transfections, virus purification
  • Excellent writing and communication skills; ability to understand and communicate scientific information; proficiency in Powerpoint, graphic displays and tables
  • A self-starter with the ability to work in a fast-paced environment and adapt quickly to changing needs and priorities; proven ability to prioritise and manage multiple tasks simultaneously